Prof. Dr. Markus Pauly

Higher plant cells are encased in cell walls that define their shape and contribute to the strength and structural integrity not only of individual cells, but also of the entire plant. The wall consists of microcrystalline cellulose that is embedded in a hydrated matrix consisting of coextensive networks of complex heteropolysaccharides and and polyphenols, such as lignin. Despite its necessary rigidity, the cell wall is a highly dynamic entity that is metabolically active. Within CEPLAS we will study the carbon flow from photosynthesis to the wall.

1. Wanke A, van Boerdonk S, Mahdi LK, Wawra S, Neidert M, Chandrasekar B, Saake P, Saur IML, Derbyshire P, Holton N, Menke FLH, Brands M, Pauly M, Acosta IF, Zipfel C, Zuccaro A (2023) A GH81-type beta-glucan-binding protein enhances colonization by mutualistic fungi in barley. Curr Biol 33(23):5071-5084 e5077. doi: 10.1016/j.cub.2023.10.048.
2. Immelmann R, Gawenda N, Ramirez V, Pauly M (2023) Identification of a xyloglucan beta-xylopyranosyltransferase from Vaccinium corymbosum. Plant Direct 7(7):e514. doi: 10.1002/pld3.514.
3. Huebbers JW, Caldarescu GA, Kubátová Z, Sabol P, Levecque SCJ, Kuhn H, Kulich I, Reinstädler A, Büttgen K, Manga-Robles A, Mélida H, Pauly M, Panstruga R, Žárský V (2023) Interplay of EXO70 and MLO proteins modulates trichome cell wall composition and susceptibility to powdery mildew. The Plant Cell 36(4):1007-1035. doi: 10.1093/plcell/koad319.
4. Perez-Anton M, Schneider I, Kroll P, Hofhuis H, Metzger S, Pauly M, Hay A (2022) Explosive seed dispersal depends on SPL7 to ensure sufficient copper for localized lignin deposition via laccases. Proc Natl Acad Sci U S A 119(24):e2202287119. doi: 10.1073/pnas.2202287119.
5. Ökmen B, Jaeger E, Schilling L, Finke N, Klemd A, Lee YJ, Wemhöner R, Pauly M, Neumann U, Doehlemann G (2022) A conserved enzyme of smut fungi facilitates cell-to-cell extension in the plant bundle sheath. Nat Commun 13(1):6003. doi: 10.1038/s41467-022-33815-7.
6. Chandrasekar B, Wanke A, Wawra S, Saake P, Mahdi L, Charura N, Neidert M, Poschmann G, Malisic M, Thiele M, Stuhler K, Dama M, Pauly M, Zuccaro A (2022) Fungi hijack a ubiquitous plant apoplastic endoglucanase to release a ROS scavenging beta-glucan decasaccharide to subvert immune responses. Plant Cell. doi: 10.1093/plcell/koac114.
7. Kraemer FJ, Lunde C, Koch M, Kuhn BM, Ruehl C, Brown PJ, Hoffmann P, Göhre V, Hake S, Pauly M, Ramírez V (2021) A mixed-linkage (1,3;1,4)-β-D-glucan specific hydrolase mediates dark-triggered degradation of this plant cell wall polysaccharide. Plant Physiology 185(4):1559-1573. doi: 10.1093/plphys/kiab009.
8. Kim S-J, Chandrasekar B, Rea AC, Danhof L, Zemelis-Durfee S, Thrower N, Shepard ZS, Pauly M, Brandizzi F, Keegstra K (2020) The synthesis of xyloglucan, an abundant plant cell wall polysaccharide, requires CSLC function. Proceedings of the National Academy of Sciences 117(33):20316-20324. doi: 10.1073/pnas.2007245117.
9. Voiniciuc C, Dama M, Gawenda N, Stritt F, Pauly M (2019) Mechanistic insights from plant heteromannan synthesis in yeast. Proc Natl Acad Sci U S A 116(2):522-527. doi: 10.1073/pnas.1814003116.
10. Pauly M, Keegstra K (2016) Biosynthesis of the Plant Cell Wall Matrix Polysaccharide Xyloglucan. Annu Rev Plant Biol 67:235-259. doi: 10.1146/annurev-arplant-043015-112222.