Genetic variation in a phenotype can be due to a single gene or a combination of genes. It is the single alleles, not the genetic interactions per se, that are heritable from parents to offspring. The latter can result in a fraction that does not either fuel the natural selection or enable artifical selection. In broad term, my project questions (1) the heritable and non-heritable components of varation in phenotype, transcriptome, and methylome in Arabidopsis lyrata model; and (2) how the genetic variation in transcription and methylation are linked to that in phenotype. To this end, we hope this knowledge can contribute to leveraging future conservation efforts and breeding strategies.