Prof. Dr. Guido Grossmann

Research focus

Our group studies mechanisms of cellular morphogenesis, growth regulation and cell-to-cell communication. A favorite study object of the lab are root hairs of plants, as we are fascinated by the robustness of their cell shape and the plasticity of their growth. We develop microdevices that enable quantitative microscopy of signaling and subcellular dynamics in growing roots in structured environments or under changing environmental conditions.

The five most important publications

  1. Denninger P, Reichelt A, Schmidt VAF, Mehlhorn DG, Asseck LY, Stanley CE, Keinath NF, Evers JF, Grefen C, Grossmann G (2019) Distinct RopGEFs Successively Drive Polarization and Outgrowth of Root Hairs. Curr Biol 29(11):1854-1865 e1855. doi: 10.1016/j.cub.2019.04.059.
  2. Stanley CE, Shrivastava J, Brugman R, Heinzelmann E, van Swaay D, Grossmann G (2018) Dual-flow-RootChip reveals local adaptations of roots towards environmental asymmetry at the physiological and genetic levels. New Phytol 217(3):1357-1369. doi: 10.1111/nph.14887.
  3. Denninger P, Bleckmann A, Lausser A, Vogler F, Ott T, Ehrhardt DW, Frommer WB, Sprunck S, Dresselhaus T, Grossmann G (2014) Male-female communication triggers calcium signatures during fertilization in Arabidopsis. Nat Commun 5:4645. doi: 10.1038/ncomms5645.
  4. Jones AM, Xuan Y, Xu M, Wang RS, Ho CH, Lalonde S, You CH, Sardi MI, Parsa SA, Smith-Valle E, Su T, Frazer KA, Pilot G, Pratelli R, Grossmann G, Acharya BR, Hu HC, Engineer C, Villiers F, Ju C, Takeda K, Su Z, Dong Q, Assmann SM, Chen J, Kwak JM, Schroeder JI, Albert R, Rhee SY, Frommer WB (2014) Border control--a membrane-linked interactome of Arabidopsis. Science 344(6185):711-716. doi: 10.1126/science.1251358.
  5. Grossmann G, Guo W-J, Ehrhardt DW, Frommer WB, Sit RV, Quake SR, Meier M (2011) The RootChip: An Integrated Microfluidic Chip for Plant Science. The Plant Cell 23(12):4234-4240. doi: 10.1105/tpc.111.092577.


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Prof. Dr. Guido Grossmann

+49 0211 81 14746

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Institute of Cell and Interaction Biology
Heinrich Heine University Düsseldorf