Prof. Dr. Michael Feldbrügge

Research focus

Plants host a substantial amount of endophytic microorganisms such as bacteria and fungi. As a member of Research Area C, we are interested in discovering novel examples for fungal endophytes interacting with species of the Brassicaceae. We aim to culture these fungi and develop DNA transformation systems to initiate molecular characterisation of these eukaryotic microorganisms. Our long term goal is the modification of such endophytes so that they gain novel properties that are beneficial for the plant. This could, for example, include novel synthetic metabolic pathways studied intensively in Research Area D.

The ten most important publications

  1. Zander S, Baumann S, Weidtkamp-Peters S, Feldbrügge M (2016) Endosomal assembly and transport of heteromeric septin complexes promote septin cytoskeleton formation. J Cell Sci 129(14):2778-2792.
  2. Pohlmann T, Baumann S, Haag C, Albrecht M, Feldbrügge M (2015) A FYVE zinc finger domain protein specifically links mRNA transport to endosome trafficking. eLife 4.
  3. Haag C, Steuten B, Feldbrügge M (2015) Membrane-Coupled mRNA Trafficking in Fungi. Annual review of microbiology 69:265-281.
  4. Jansen RP, Niessing D, Baumann S, Feldbrügge M (2014) mRNA transport meets membrane traffic. Trends in genetics : TIG 30(9):408-417.
  5. Baumann S, König J, Koepke J, Feldbrügge M (2014) Endosomal transport of septin mRNA and protein indicates local translation on endosomes and is required for correct septin filamentation. EMBO reports 15(1):94-102.
  6. Feldbrügge M, Kellner R, Schipper K (2013) The biotechnological use and potential of plant pathogenic smut fungi. Applied microbiology and biotechnology 97(8):3253-3265.
  7. Baumann S, Pohlmann T, Jungbluth M, Brachmann A, Feldbrügge M (2012) Kinesin-3 and dynein mediate microtubule-dependent co-transport of mRNPs and endosomes. J Cell Sci 125(Pt 11):2740-2752.
  8. Koepke J, Kaffarnik F, Haag C, Zarnack K, Luscombe NM, König J, Ule J, Kellner R, Begerow D, Feldbrügge M (2011) The RNA-binding protein Rrm4 is essential for efficient secretion of endochitinase Cts1. Mol Cell Proteomics 10(12):M111 011213.
  9. Konig J, Baumann S, Koepke J, Pohlmann T, Zarnack K, Feldbrügge M (2009) The fungal RNA-binding protein Rrm4 mediates long-distance transport of ubi1 and rho3 mRNAs. EMBO J 28(13):1855-1866.
  10. Kämper J, Kahmann R, Bölker M, Ma LJ, Brefort T, Saville BJ, Banuett F, Kronstad JW, Gold SE, Müller O, Perlin MH, Wösten HA, de Vries R, Ruiz-Herrera J, Reynaga-Peña CG, Snetselaar K, McCann M, Pérez-Martín J, Feldbrügge M, Basse CW, Steinberg G, Ibeas JI, Holloman W, Guzman P, Farman M, Stajich JE, Sentandreu R, González-Prieto JM, Kennell JC, Molina L, Schirawski J, Mendoza-Mendoza A, Greilinger D, Münch K, Rössel N, Scherer M, Vraneš M, Ladendorf O, Vincon V, Fuchs U, Sandrock B, Meng S, Ho EC, Cahill MJ, Boyce KJ, Klose J, Klosterman SJ, Deelstra HJ, Ortiz-Castellanos L, Li W, Sanchez-Alonso P, Schreier PH, Häuser-Hahn I, Vaupel M, Koopmann E, Friedrich G, Voss H, Schlüter T, Margolis J, Platt D, Swimmer C, Gnirke A, Chen F, Vysotskaia V, Mannhaupt G, Güldener U, Münsterkötter M, Haase D, Oesterheld M, Mewes HW, Mauceli EW, DeCaprio D, Wade CM, Butler J, Young S, Jaffe DB, Calvo S, Nusbaum C, Galagan J, Birren BW (2006) Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis. Nature 444(7115):97-101.
Prof. Dr. Michael Feldbrügge
CEPLAS Michael Feldbrügge

feldbrue[at]hhu.de

 +49 211 81-14720

Institute of Microbiology
Heinrich Heine University Düsseldorf

Universitätsstraße 1

40225 Düsseldorf

www.mikrobiologie.hhu.de

Heinrich Heine University
University of Cologne
Max Planck Institute for Plant Breeding Research
Forschungszentrum Jülich