PD. Dr. Tamara Gigolashvili

Research focus

Plant secondary metabolites play critical roles in the interaction of plants with their environment. To better understand the fundamental biology of plant-microbiome interactions, we aim at identifying novel “metabolic regulons”, including transcription factors, biosynthetic enzymes and transporter proteins, which are important in the production of secondary metabolites shaping endophytic community of plants in the rizosphere. Once identified, the regulon will be introduced into a “synthetic plant”, which will correspondingly lack or overproduce specific bioactive metabolites in roots and will therefore manifest beneficial interactions with the plant microbial community.

The ten most important publications

  1. Frerigmann H, Pislewska-Bednarek M, Sánchez-Vallet A, Molina A, Glawischnig E, Gigolashvili T, Bednarek P (2016) Regulation of Pathogen-Triggered Tryptophan Metabolism in Arabidopsis thaliana by MYB Transcription Factors and Indole Glucosinolate Conversion Products. Molecular plant 9(5):682-695.
  2. Chan KX, Mabbitt PD, Phua SY, Mueller JW, Nisar N, Gigolashvili T, Stroeher E, Grassl J, Arlt W, Estavillo GM, Jackson CJ, Pogson BJ (2016) Sensing and signaling of oxidative stress in chloroplasts by inactivation of the SAL1 phosphoadenosine phosphatase. Proc Natl Acad Sci U S A 113(31):E4567-4576.
  3. Zhao Y, Wang J, Liu Y, Miao H, Cai C, Shao Z, Guo R, Sun B, Jia C, Zhang L, Gigolashvili T, Wang Q (2015) Classic myrosinase-dependent degradation of indole glucosinolate attenuates fumonisin B1-induced programmed cell death in Arabidopsis. Plant J 81(6):920-933.
  4. Kottb M, Gigolashvili T, Grosskinsky DK, Piechulla B (2015) Trichoderma volatiles effecting Arabidopsis: from inhibition to protection against phytopathogenic fungi. Frontiers in microbiology 6:995.
  5. Frerigmann H, Glawischnig E, Gigolashvili T (2015) The role of MYB34, MYB51 and MYB122 in the regulation of camalexin biosynthesis in Arabidopsis thaliana. Front Plant Sci 6:654.
  6. Frerigmann H, Gigolashvili T (2014) MYB34, MYB51, and MYB122 distinctly regulate indolic glucosinolate biosynthesis in Arabidopsis thaliana. Molecular plant 7(5):814-828.
  7. Frerigmann H, Berger B, Gigolashvili T (2014) bHLH05 is an interaction partner of MYB51 and a novel regulator of glucosinolate biosynthesis in Arabidopsis. Plant Physiol 166(1):349-369.
  8. Benstein RM, Ludewig K, Wulfert S, Wittek S, Gigolashvili T, Frerigmann H, Gierth M, Flügge UI, Krueger S (2013) Arabidopsis phosphoglycerate dehydrogenase1 of the phosphoserine pathway is essential for development and required for ammonium assimilation and tryptophan biosynthesis. The Plant cell 25(12):5011-5029.
  9. Gigolashvili T, Geier M, Ashykhmina N, Frerigmann H, Wulfert S, Krueger S, Mugford SG, Kopriva S, Haferkamp I, Flügge UI (2012) The Arabidopsis thylakoid ADP/ATP carrier TAAC has an additional role in supplying plastidic phosphoadenosine 5'-phosphosulfate to the cytosol. The Plant cell 24(10):4187-4204.
  10. Aarabi F, .... (Science (in press).
Dr. Tamara Gigolashvili
CEPLAS Tamara Gigolashvili


 +49 221 470-6596

Botanical Institute, Cologne Biocenter
University of Cologne

Zülpicher Straße 47b

50829 Cologne


Heinrich Heine University
University of Cologne
Max Planck Institute for Plant Breeding Research
Forschungszentrum Jülich